4-Benzyl-5-methyl-[1,4]oxazepane → 4-Benzyl-5-phenyl-1,4-oxazepane

HRID 515448노트

반응식

C(N1C(C)CCOCC1)C1C=CC=CC=1.[CH2:16]([N:23]1[CH:29]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH2:28][CH2:27][O:26][CH2:25][C:24]1=O)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([N:23]1[CH:29]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1)[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

참가 물질

반응물 2

HCID 667187904-Benzyl-5-methyl-[1,4]oxazepane

HCID 672829204-Benzyl-5-phenyl-[1,4]oxazepan-3-one

생성물 1

HCID 667185434-Benzyl-5-phenyl-1,4-oxazepane

실험 절차

4-Benzyl-5-phenyl-[1,4]oxazepane was prepared by the same procedure as that of 4-benzyl-5-methyl-[1,4]oxazepane except for utilizing 4-benzyl-5-phenyl-[1,4]oxazepan-3-one instead of 4-benzyl-5-methyl-[1,4]oxazepan-3-one. 4-Benzyl-5-phenyl-[1,4]oxazepane was obtained as colorless oil (0.28 g, 1.0 mmol, 39%).

출처 및 근거

ORD 기록: ord-402bd8e6445e45ddbe5ba70a43319047
출처 데이터셋: uspto-grants-2015_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09108957B2

반응 노트

불러오는 중…