Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methylbenzaldehyde → 3-(2-Aminoethyl)-5-[(4-methylphenyl)methylidene]-1,3-thiazolidine-2,4-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methylbenzaldehyde | HCID 7725 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 3-(2-Aminoethyl)-5-(phenylmethylidene)-1,3-thiazolidine-2,4-dione | HCID 1551244 | — |
| 반응물 | 3-(2-(Tritylamino)ethyl)thiazolidine-2,4-dione | HCID 71697168 | — |
| 생성물 | 3-(2-Aminoethyl)-5-[(4-methylphenyl)methylidene]-1,3-thiazolidine-2,4-dione | HCID 2432691 | — |
반응 단계
The title compound 30d was prepared from 4-methylbenzaldehyde (73 μL, 0.62 mmol), compound 29 (250 mg, 0.62 mmol) and piperidine (7.0 μL, 0.062 mmol) in a manner similar to that described for 30a in 36.0% (83 mg) yield as a cream solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09115122B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-2f931743f34044309890919c7d598b28 |
| 출처 메모 | uspto-grants-2015_08 |