Piperidine → HCID 71697766, 화합물

HRID 517616

반응식

HRID 517616 반응식
[CH2:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)[CH2:2][CH3:3].C([NH:31][CH2:32][CH2:33][N:34]1[C:38](=[O:39])[CH2:37][S:36][C:35]1=[O:40])(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.N1CCCCC1.NCCN1C(=O)/C(=C/C2C=CC=CC=2)/SC1=O>>[NH2:31][CH2:32][CH2:33][N:34]1[C:38](=[O:39])/[C:37](=[CH:8]/[C:7]2[CH:10]=[CH:11][C:4]([CH2:1][CH2:2][CH3:3])=[CH:5][CH:6]=2)/[S:36][C:35]1=[O:40]

참가 물질

5

반응물 4

HCID 8082PiperidineHCID 1200474-PropylbenzaldehydeHCID 15512443-(2-Aminoethyl)-5-(phenylmethylidene)-1,3-thiazolidine-2,4-dioneHCID 716971683-(2-(Tritylamino)ethyl)thiazolidine-2,4-dione

생성물 1

HCID 71697766HCID 71697766, 화합물

실험 절차

The title compound 30e was prepared from 4-propylbenzaldehyde (92 mg, 0.62 mmol), compound 29 (250 mg, 0.62 mmol) and piperidine (7.0 μL, 0.062 mmol) in a manner similar to that described for 30a in 38.0% (95 mg) yield as a white solid.

후처리

  1. customyield as a white solid

출처 및 근거

ORD 기록
ord-3b75a28e711541b9903416cd887909a1
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09115122B2

연결된 노트

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