2-Bromo-1-fluoro-4-(methylsulfonyl)benzene → 8-(2-Fluoro-5-methylsulfonylphenyl)-6-methylpyrido[4,3-d]pyrimidin-5-one
반응식
Br[C:2]1[CH:7]=[C:6]([S:8]([CH3:11])(=[O:10])=[O:9])[CH:5]=[CH:4][C:3]=1[F:12].BrC1C=C(S(CC)(=O)=O)C=CC=1OCCC.FC1C=CC(S(C)(=O)=O)=CC=1B1OC(C)(C)C(C)(C)O1.Br[C:50]1[C:55]2[N:56]=[CH:57][N:58]=[CH:59][C:54]=2[C:53](=[O:60])[N:52]([CH3:61])[CH:51]=1>>[F:12][C:3]1[CH:4]=[CH:5][C:6]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:7][C:2]=1[C:50]1[C:55]2[N:56]=[CH:57][N:58]=[CH:59][C:54]=2[C:53](=[O:60])[N:52]([CH3:61])[CH:51]=1참가 물질
5
