3-Morpholino-1-propanol → HCID 178457854, 화합물

HRID 518699

반응식

HRID 518699 반응식
[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][CH2:9][OH:10])[CH2:3][CH2:2]1.[CH:11]([NH:14][C:15]([C@H:17]1[CH2:22][CH2:21][C@@H:20]([NH:23][C:24]2[C:29]([N+:30]([O-:32])=[O:31])=[CH:28][N:27]=[C:26](OCCOC)[CH:25]=2)[CH2:19][CH2:18]1)=[O:16])([CH3:13])[CH3:12]>>[CH:11]([NH:14][C:15]([C@H:17]1[CH2:18][CH2:19][C@@H:20]([NH:23][C:24]2[C:29]([N+:30]([O-:32])=[O:31])=[CH:28][N:27]=[C:26]([O:10][CH2:9][CH2:8][CH2:7][N:4]3[CH2:5][CH2:6][O:1][CH2:2][CH2:3]3)[CH:25]=2)[CH2:21][CH2:22]1)=[O:16])([CH3:13])[CH3:12]

참가 물질

3

반응물 2

HCID 1995763-Morpholino-1-propanolHCID 178496145HCID 178496145, 화합물

생성물 1

HCID 178457854HCID 178457854, 화합물

실험 절차

Intermediate cis-N-isopropyl-4-(2-(3-morpholinopropoxy)-5-nitropyridin-4-ylamino)cyclohexanecarboxamide was prepared with 3-morpholinopropan-1-ol using a 2 step procedure analogous to that used to prepare cis-N-isopropyl-4-(2-(2-methoxyethoxy)-5-nitropyridin-4-ylamino)cyclohexanecarboxamide (200 mg).

출처 및 근거

ORD 기록
ord-736659e4ec254203b671f45fd535e70a
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09115127B2

연결된 노트

불러오는 중…