Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 4'-(Trifluoromethyl)(1,1'-biphenyl)-2-carboxylic acid | HCID 55251 | — |
| 생성물 | 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonyl chloride | HCID 11066000 | 99% |
반응 단계
4′-Trifluoromethyl-biphenyl-2-carboxylic acid (25 g, 94 mmol) was combined with thionyl chloride (35 ml, 470 mmol) and the mixture was heated at reflux. After 2 h, the mixture was concentrated under vacuum to afford 26.5 g of the title product as a light yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713489B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-e31257c66ddc4875b0e298998fa41e5a |
| 출처 메모 | uspto-grants-2004_03 |