Pyrrole-2-Carboxylic Acid → N-{4-[4-(1-Pyrrolidinylmethyl)-2-pyridyloxy]-cis-2-butenyl}pyrrole-2-carboxamide

HRID 52072

반응식

HRID 52072 반응식
[N:1]1([CH2:6][C:7]2[CH:12]=[CH:11][N:10]=[C:9]([O:13][CH2:14]/[CH:15]=[CH:16]\[CH2:17][NH2:18])[CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:19]1[CH:23]=[CH:22][CH:21]=[C:20]1[C:24](O)=[O:25]>>[N:1]1([CH2:6][C:7]2[CH:12]=[CH:11][N:10]=[C:9]([O:13][CH2:14]/[CH:15]=[CH:16]\[CH2:17][NH:18][C:24]([C:20]3[NH:19][CH:23]=[CH:22][CH:21]=3)=[O:25])[CH:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

3

실험 절차

Following a procedure similar to that described in Example 13, but using 4-[4-(1-pyrrolidinylmethyl)-2-pyridyloxy]-cis-2-butenylamine and 2-pyrrolecarboxylic acid as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as a white powder, melting at 124°-127° C., in a 64% yield.

출처 및 근거

ORD 기록
ord-ddf79f2076d94130af203327baba4759
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05616579

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