4-Methyl-3-nitrobenzenesulfonyl chloride → N-[5-chloro-2-(methylthio)phenyl]-4-methyl-3-nitrobenzenesulfonamide

HRID 520916노트

반응식

HRID 520916 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH2:8])[CH:7]=1.[CH3:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][C:13]=1[N+:22]([O-:24])=[O:23]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH:8][S:18]([C:15]2[CH:16]=[CH:17][C:12]([CH3:11])=[C:13]([N+:22]([O-:24])=[O:23])[CH:14]=2)(=[O:19])=[O:20])[CH:7]=1

참가 물질

3

반응물 2

HCID 5606384-Methyl-3-nitrobenzenesulfonyl chlorideHCID 27945775-Chloro-2-(methylthio)aniline

생성물 1

HCID 57378643N-[5-chloro-2-(methylthio)phenyl]-4-methyl-3-nitrobenzenesulfonamide수율 61%

실험 절차

Following General Procedure B, the title compound (197 mg, 61%) was prepared from 5-Chloro-2-methylsulfanyl-phenylamine (150 mg, 0.87 mmol) and 4-Methyl-3-nitro-benzenesulfonyl chloride (235 mg, 0.87 mmol).

출처 및 근거

ORD 기록
ord-31a752390bbd4905886a8e3585ba1118
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09328067B2

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