Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isobutyryl chloride → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-[2-(2-methylpropionyloxy)ethylthio]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isobutyryl chloride | HCID 62325 | — |
| 반응물 | N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamide | HCID 67725880 | — |
| 생성물 | N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-[2-(2-methylpropionyloxy)ethylthio]acetamide | HCID 67725820 | 73% |
반응 단계
Following a procedure similar to that described in Example 7, but using N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-2-(2-hydroxyethylthio)acetamide (prepared as described in Example 1) and 2-methylpropionyl chloride as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a 73% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616579 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-37f66a6f2d5848f6aa6921bcb005933c |
| 출처 메모 | uspto-grants-1997_04 |