3,4-dihydro-2H-pyran → 2H-Pyran, 2-(4-chlorobutoxy)tetrahydro-

참여 물질

역할	이름	HCID	투입량
반응물	3,4-dihydro-2H-pyran	HCID 8080	—
반응물	4-Chloro-1-butanol	HCID 13569	—
촉매	Hydrochloric Acid	HCID 313	—
생성물	2H-Pyran, 2-(4-chlorobutoxy)tetrahydro-	HCID 170488	89.9%

반응 단계

Dihydropyran (15.5 g) was added dropwise to a mixture of 4-chlorobutanol (20 g) and hydrochloric acid (18 M, 1 drop) at RT. The mixture was stirred for 30 min and washed with H2O (100 ml), aqueous NaHCO3 (1 M, 50 ml) and BR (50 ml). The dried liquid was heated under reduced pressure to leave the title compound as a colourless liquid (31.9 g). T.l.c. [L] Rf 0.5.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US05243076
출처 데이터셋	uspto-grants-1993_09
ORD ID	ord-8d888550453845d89f366f2eeaefe39f
출처 메모	uspto-grants-1993_09