Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminostyrene → 1-(4-Vinylphenyl)-3-[3,5-bis(trifluoromethyl)phenyl]thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminostyrene | HCID 73700 | — |
| 반응물 | 3,5-Bis(trifluoromethyl)phenyl isothiocyanate | HCID 2733395 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-(4-Vinylphenyl)-3-[3,5-bis(trifluoromethyl)phenyl]thiourea | HCID 58112444 | 60% |
반응 단계
To a stirred solution of 4-aminostyrene (3.5 mmol) in dry THF (20 mL) under nitrogen was added 3,5-bis-(trifluoromethyl)phenyl isothiocyanate (3.5 mmol). The solution was refluxed overnight and then the solvent was evaporated under reduced pressure. The resulting solid residue was purified by column chromatography to yield the desired product in 60% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09329186B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-3fe51d0a917048c28d43fc50b0e7264a |
| 출처 메모 | uspto-grants-2016_05 |