Dithiooxamide → 2,5-Bis(3-tetradecoxycarbonyl-2-thienyl)-thiazolo[5,4-d]thiazole

HRID 523440노트

반응식

HRID 523440 반응식
[CH2:1]([O:15][C:16]([C:18]1[CH:22]=[CH:21][S:20][C:19]=1[CH:23]=O)=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[NH2:25][C:26]([C:28]([NH2:30])=[S:29])=[S:27]>>[CH2:1]([O:15][C:16]([C:18]1[CH:22]=[CH:21][S:20][C:19]=1[C:23]1[S:27][C:26]2[N:25]=[C:23]([C:19]3[S:20][CH:21]=[CH:22][C:18]=3[C:16]([O:15][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])=[O:17])[S:29][C:28]=2[N:30]=1)=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

참가 물질

3

반응물 2

HCID 2777982DithiooxamideHCID 86717684Tetradecyl-2-formylthiophene-3-carboxylate

생성물 1

HCID 672935452,5-Bis(3-tetradecoxycarbonyl-2-thienyl)-thiazolo[5,4-d]thiazole

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온도
200 °C

실험 절차

To a 25 mL flask were added 0.978 g (2.8 mmol) of tetradecyl-2-formylthiophene-3-carboxylate and 110 mg (0.9 mmol) of dithiooxamide. This mixture was heated to 200° C. for 2 hours. The resulting mixture was purified by column chromatography using a mixture of hexane and dichloromethane to give the desired compound. The NMR data were obtained and were consistent with those of the desired compound.

후처리

  1. customThe resulting mixture was purified by column chromatography
  2. additiona mixture of hexane and dichloromethane

출처 및 근거

ORD 기록
ord-2c570901f56a42438a3ee8151bf3eb2f
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09337358B2

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