Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2-Chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione → 1-(5-Amino-2-chloro-4-fluorophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2-Chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione | HCID 57280332 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Platinum | HCID 23939 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 1-(5-Amino-2-chloro-4-fluorophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione | HCID 10935060 | — |
반응 단계
A mixture of 1-(2-chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione (28.5 g, 0.09 mol) and 5% platinum on activated carbon (1 g) in ethyl acetate is hydrogenated at 55 psi until hydrogen uptake is complete. The reaction mixture is then filtered and concentrated in vacuo to give the title product as a white solid, mp 244°-245° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616706 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-f01dc30df53843838603cbb2252ed02f |
| 출처 메모 | uspto-grants-1997_04 |