Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Morpholinecarboxylic acid → HCID 90043251, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Morpholinecarboxylic acid | HCID 3340152 | — |
| 반응물 | Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(1,3,4-thiadiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate | HCID 90043754 | — |
| 생성물 | HCID 90043251 | HCID 90043251 | 56% |
반응 단계
Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-2-(1,3,4-thiadiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (0.7 g, 1.5 mmol) was reacted with morpholine-3-carboxylic acid (0.2 g, 1.5 mmol) according to the procedure as described in Example 1, Step C to give the title compound as a yellow solid (0.44 g, 56%). The compound was characterized by the following spectroscopic data:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09340538B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-c3e072d42c294a39b275f74452168be5 |
| 출처 메모 | uspto-grants-2016_05 |