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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 525033생성일: 2026년 10월 25일

O-Benzyl-N-(tert-butoxycarbonyl)-L-homoserine → (S)-tert-Butyl 4-(benzyloxy)-1-oxo-1-(2-(phenylcarbamoyl)-1H-pyrrol-1-ylamino)butan-2-ylcarbamate

https://huagongshe.com/reaction/525033

반응식

참여 물질

역할이름HCID투입량
반응물O-Benzyl-N-(tert-butoxycarbonyl)-L-homoserineHCID 15058464—
반응물1-amino-N-phenyl-1H-pyrrole-2-carboxamideHCID 70922454—
생성물(S)-tert-Butyl 4-(benzyloxy)-1-oxo-1-(2-(phenylcarbamoyl)-1H-pyrrol-1-ylamino)butan-2-ylcarbamateHCID 8672205299.6%

반응 단계

The title compound was prepared from 1-amino-N-phenyl-1H-pyrrole-2-carboxamide (0.65 g, 3.2 mmol) and (S)-4-(benzyloxy)-2-(tert-butoxycarbonylamino)butanoic acid (1.0 g, 3.2 mmol) following the experimental procedure described in Preparation 73a. 1.57 g (96% yield) of the desired compound were obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09340547B2
출처 데이터셋uspto-grants-2016_05
ORD IDord-46b1e72f7fd44e81986c33a8b9028987
출처 메모uspto-grants-2016_05