Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(2Indenyl)indole → 6-Oxo carbazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(2Indenyl)indole | HCID 10585619 | — |
| 반응물 | Ethyl (2Z)-3-cyanoprop-2-enoate | HCID 15577688 | — |
| 용매 | Toluene | HCID 1140 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Trifluoroacetic acid | HCID 6422 | — |
| 용매 | Diethylaluminum chloride | HCID 7277 | — |
| 용매 | Ethylaluminum dichloride | HCID 11237 | — |
| 용매 | Tin tetrachloride | HCID 24287 | — |
| 용매 | Aluminum(III) Chloride | HCID 6451240 | — |
| 생성물 | 6-Oxo carbazole | HCID 18980403 | — |
반응 단계
In Method B (FIG. 2), a 2-(heteroaryl)indole derivative (1-3), or 2-(aryl)indole derivative such as 2-(2-indenyl)indole 4 is reacted with ethyl cis-β-cyanoacrylate in the presence of a catalyst such as SnCl4, AlCl3, EtAlCl2, Et2AlCl or TFA in CH2Cl2, C2H4Cl2 or toluene as solvent to give the 6-oxo carbazole compounds of formula I of the invention.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616724 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-7186f49c7b7e4d1fbb08b8b3540eddf4 |
| 출처 메모 | uspto-grants-1997_04 |