Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2,4-Diaminoquinazoline-6-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Potassium Cyanide | HCID 9032 | — |
| 반응물 | 2,4,6-Triaminoquinazoline | HCID 292661 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 촉매 | Copper sulfate pentahydrate | HCID 24463 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2,4-Diaminoquinazoline-6-carbonitrile | HCID 282699 | — |
반응 단계
The 2,4,6-triaminoquinazoline derivatives described above may then optionally be treated with 2N hydrochloric acid, sodium nitrite, potassium cyanide, and copper(II) sulfate pentahydrate in water, affording the corresponding 2,4-diamino-6-cyanoquinazoline, for example, 2,4-diamino-6-cyano-5-methylquinazoline. Step A of Example 14 describes in detail this step in the reaction sequence.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616718 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-7093a7fae48f41c8aee7b43ad15a91f4 |
| 출처 메모 | uspto-grants-1997_04 |