Cesium carbonate → Tert-butyl 4-(3-((R)-3-(((S)-3-(tert-butoxy)-3-oxo-1-(4-(2-(tosyloxy)ethoxy)phenyl)propyl)carbamoyl)piperidin-1-YL)-3-oxopropyl)piperidine-1-carboxylate

반응식

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16]([N:18]2[CH2:23][CH2:22][CH2:21][C@@H:20]([C:24](=[O:42])[NH:25][C@H:26]([C:35]3[CH:40]=[CH:39][C:38]([OH:41])=[CH:37][CH:36]=3)[CH2:27][C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[CH2:19]2)=[O:17])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C(=O)([O-])[O-].[Cs+].[Cs+].[C:49]1([CH3:72])[CH:54]=[CH:53][C:52]([S:55]([O:58][CH2:59][CH2:60]OS(C2C=CC(C)=CC=2)(=O)=O)(=[O:57])=[O:56])=[CH:51][CH:50]=1>CN(C)C=O>[C:31]([O:30][C:28](=[O:29])[CH2:27][C@H:26]([NH:25][C:24]([C@@H:20]1[CH2:21][CH2:22][CH2:23][N:18]([C:16](=[O:17])[CH2:15][CH2:14][CH:11]2[CH2:10][CH2:9][N:8]([C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])[CH2:13][CH2:12]2)[CH2:19]1)=[O:42])[C:35]1[CH:40]=[CH:39][C:38]([O:41][CH2:60][CH2:59][O:58][S:55]([C:52]2[CH:53]=[CH:54][C:49]([CH3:72])=[CH:50][CH:51]=2)(=[O:57])=[O:56])=[CH:37][CH:36]=1)([CH3:32])([CH3:33])[CH3:34]