Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl N-[(1R,3S)-3-benzyloxycarbonylaminocyclohexyl]carbamate → methyl N-[(1R,3S)-3-aminocyclohexyl]carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl N-[(1R,3S)-3-benzyloxycarbonylaminocyclohexyl]carbamate | HCID 68007620 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | methyl N-[(1R,3S)-3-aminocyclohexyl]carbamate | HCID 68007555 | — |
반응 단계
Methyl N-[(1R,3S)-3-benzyloxycarbonylaminocyclohexyl]carbamate, 19a, (1.09 g, 3.56 mmol) was dissolved in ethanol (100 mL) and treated with 10% Pd/C (0.38 g, 0.36 mmol). The flask was capped, degassed and fitted with a hydrogen balloon and allowed to stir overnight. The reaction mixture was filtered under nitrogen and concentrated in vacuo to provide the product, 19b, as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09345708B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-5b52f1104d674f1d9ba44f11813148a8 |
| 출처 메모 | uspto-grants-2016_05 |