Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Ethyl 2-isopropylthiazole-5-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Hexane | HCID 8058 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | 2-Methylpropanethioamide | HCID 10909507 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Ethyl 2-isopropylthiazole-5-carboxylate | HCID 10608068 | 83% |
반응 단계
Using the procedure of Example 1J but replacing thioformamide with 2-methylpropane-thioamide provided, after silica gel chromatography using 9:1 ethyl acetate:hexane, the desired compound, Rf 0.8, (5% methanol in chloroform) in 83% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616720 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-3615544b7697404c86ec6836a57e781d |
| 출처 메모 | uspto-grants-1997_04 |