Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl (3-amino-4-fluorophenyl)carbamate → Tert-butyl (4-fluoro-3-((5-formyl-2-(methylthio)pyrimidin-4-yl)amino)phenyl)carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl (3-amino-4-fluorophenyl)carbamate | HCID 11790890 | — |
| 반응물 | Tert-butyl (3-((5-formyl-2-(methylthio)pyrimidin-4-yl)amino)phenyl)carbamate | HCID 57343702 | — |
| 생성물 | Tert-butyl (4-fluoro-3-((5-formyl-2-(methylthio)pyrimidin-4-yl)amino)phenyl)carbamate | HCID 86732013 | — |
반응 단계
The title compound was prepared according to the procedures described for Intermediate 50, starting from tert-butyl (3-amino-4-fluorophenyl)carbamate (58a; prepared according to the reported protocol in Kuramoto, Y. et al. J. Med. Chem. 2003, 46, 1905-1917).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09346801B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-f3f635878b4e4830a14a31b0091e706e |
| 출처 메모 | uspto-grants-2016_05 |