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HRID 5285생성일: 2026년 10월 23일

Flurbiprofen → 2-Hydroxyethyl Methacrylate

https://huagongshe.com/ko/reaction/5285

반응식

참여 물질

역할이름HCID투입량
반응물FlurbiprofenHCID 3394—
반응물Neomycin SulfateHCID 197162—
반응물Dexamethasone 21-(sodium hydrogen phosphate)HCID 23667621—
반응물HCID 178418625HCID 178418625—
생성물2-Hydroxyethyl MethacrylateHCID 13360—

반응 단계

A mixture was prepared by combining aprotinin 1 g.; elastatinal 0.1 g.; flurbiprofen 0.1 g.; dexamethasone sodium phosphate 0.1 g.; neomycin sulfate; and physiological saline up to 100 g. A contact lens form the crosslinked polymer of 2-hydroxyethyl methacrylate (38 percent by weight of equilibrium water) was swelled in the given solution for 24 hours. The contact lens was used for the treatment of nonhealing corneal erosions. Within a week after application the reepithalization was sped up. Extraordinary results were attained after severe etching and burning of the anterior segment of the eye. The intraocular inflammation did not develop, the cornea did not exhibit ulceration and healed with a scar to place within a month. The transparency recovered in the periphery of the cornea.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05244673
출처 데이터셋uspto-grants-1993_09
ORD IDord-e39f5bba0a6d4f2e88f4a74a2a9aada9
출처 메모uspto-grants-1993_09