참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Flurbiprofen | HCID 3394 | — |
| 반응물 | Neomycin Sulfate | HCID 197162 | — |
| 반응물 | Dexamethasone 21-(sodium hydrogen phosphate) | HCID 23667621 | — |
| 반응물 | HCID 178418625 | HCID 178418625 | — |
| 생성물 | 2-Hydroxyethyl Methacrylate | HCID 13360 | — |
반응 단계
A mixture was prepared by combining aprotinin 1 g.; elastatinal 0.1 g.; flurbiprofen 0.1 g.; dexamethasone sodium phosphate 0.1 g.; neomycin sulfate; and physiological saline up to 100 g. A contact lens form the crosslinked polymer of 2-hydroxyethyl methacrylate (38 percent by weight of equilibrium water) was swelled in the given solution for 24 hours. The contact lens was used for the treatment of nonhealing corneal erosions. Within a week after application the reepithalization was sped up. Extraordinary results were attained after severe etching and burning of the anterior segment of the eye. The intraocular inflammation did not develop, the cornea did not exhibit ulceration and healed with a scar to place within a month. The transparency recovered in the periphery of the cornea.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05244673 |
|---|
| 출처 데이터셋 | uspto-grants-1993_09 |
|---|
| ORD ID | ord-e39f5bba0a6d4f2e88f4a74a2a9aada9 |
|---|
| 출처 메모 | uspto-grants-1993_09 |
|---|