Butanal → HCID 15638290, 화합물

HRID 528909

반응식

HRID 528909 반응식
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][NH2:12].[CH:13](=O)[CH2:14][CH2:15][CH3:16]>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][NH:12][CH2:13][CH2:14][CH2:15][CH3:16]

참가 물질

3

반응물 2

HCID 261ButanalHCID 1372821-(2-Naphthyl)methanamine

생성물 1

HCID 15638290HCID 15638290, 화합물수율 15%

실험 절차

Following a procedure analogous to that for the synthesis of Intermediate 137, 2-naphthalenemethanamine (500 mg, 3.18 mmol) and butyraldehyde (315 μL, 3.50 mmol) were converted to the title compound (100 mg, 15%). 1H NMR (CDCl3) δ 7.87-7.78 (m, 4H), 7.78-7.69 (br s, 1H), 7.56 (dd, J=8.4, 1.5 Hz, 1H), 7.52-7.43 (m, 2H), 4.06 (s, 2H), 2.78-2.69 (m, 2H), 1.65 (dt, J=15.4, 7.6 Hz, 2H), 1.38-1.23 (m, 2H), 0.88 (t, J=7.4 Hz, 3H); MS(ESI+) m/z 214.1 (M+H)+.

출처 및 근거

ORD 기록
ord-5e2ec3ae082c4db29c395ef1f9a3dd8e
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09346795B2

연결된 노트

불러오는 중…