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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 528929생성일: 2026년 10월 26일

N,N-dibutyl-4-chloro-5-methyl-1H-pyrazole-3-carboxamide → N,N-Dibutyl-5-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-pyrazole-3-carboxamide

https://huagongshe.com/reaction/528929

반응식

참여 물질

역할이름HCID투입량
반응물N,N-dibutyl-4-chloro-5-methyl-1H-pyrazole-3-carboxamideHCID 71062189—
반응물Ethyl 5-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-pyrazole-3-carboxylateHCID 71062309—
생성물N,N-Dibutyl-5-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-pyrazole-3-carboxamideHCID 7106246883%

반응 단계

Following a procedure analogous to that for the synthesis of Intermediate 1B, ethyl 5-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-pyrazole-3-carboxylate (2.15 g, 8.01 mmol) was converted to the title compound (2.35 g, 83%). MS(ESI+) m/z 352.4 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09346795B2
출처 데이터셋uspto-grants-2016_05
ORD IDord-283cc6188a734fbb81716f84ca8a64f2
출처 메모uspto-grants-2016_05