Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glycine ethyl ester, hydrochloride → N-Ethoxycarbonylmethyl-2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-hydroxymethylimidazole-5-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glycine ethyl ester, hydrochloride | HCID 2723640 | — |
| 반응물 | Succinimido 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-hydroxymethylimidazole-5-carboxylate | HCID 19036239 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | N-Ethoxycarbonylmethyl-2-butyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-hydroxymethylimidazole-5-carboxamide | HCID 19036286 | — |
반응 단계
Following a procedure similar to that described in Example 53, but using 0.307 g of succinimido 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-hydroxymethylimidazole-5-carboxylate [prepared as described in Example 52(a)], 89 mg of ethyl glycinate hydrochloride and 0.089 ml of triethylamine, 0.202 g of the
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05616599 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-d8ae651d28ae461294e4f692d26523fc |
| 출처 메모 | uspto-grants-1997_04 |