Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → Ethyl 5-ethoxy-1H-pyrazole-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Ethyl 4,4,4-trichloro-3-oxobutyrate | HCID 77294 | — |
| 반응물 | Hydrazinium chloride | HCID 115031 | — |
| 생성물 | Ethyl 5-ethoxy-1H-pyrazole-3-carboxylate | HCID 68571888 | — |
반응 단계
4,4,4-Trichloro-3-oxo-butyric acid ethyl ester (Int 8, 1 eq) and H2NNH2.HCl (1.1 eq) are mixed in EtOH. The resulting mixture is refluxed overnight. The mixture is then evaporated and the obtained crude is purified by chromatography to give Int 9 and 5-ethoxy-2H-pyrazole-3-carboxylic acid ethyl ester (Int 10).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09351955B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-71b12c252fd04dada538bd59c20bb483 |
| 출처 메모 | uspto-grants-2016_05 |