HCID 178441657, 화합물 → HCID 178441749, 화합물

반응식

[C:1]([C:4]1[N:5]=[C:6]([CH2:11][CH2:12][CH2:13][CH3:14])[NH:7][C:8]=1[C:9]#[N:10])(=[O:3])[CH3:2].[CH2:15]([Mg]Br)[CH2:16]C>>[CH2:11]([C:6]1[NH:7][C:8]([C:9]#[N:10])=[C:4]([C:1](=[O:3])[CH2:2][CH2:15][CH3:16])[N:5]=1)[CH2:12][CH2:13][CH3:14]

참가 물질

반응물 2

HCID 178441657HCID 178441657, 화합물

HCID 178455851HCID 178455851, 화합물

생성물 1

HCID 178441749HCID 178441749, 화합물수율 57.2%

실험 절차

Following a procedure similar to that described in Preparation 24(i), but using propylmagnesium bromide instead of methylmagnesium bromide, the title compound, melting at 91°-92° C., was obtained in a 57.2% yield.

출처 및 근거

ORD 기록: ord-ecc066aa9b944033836e3bcde809b0b8
출처 데이터셋: uspto-grants-1997_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05616599

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