Chloromethyl isopropyl carbonate → HCID 178440082, 화합물

HRID 53040노트

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HRID 53040 반응식
OC(C1N=C(CCC)NC=1C(OCOC(=O)C(C)(C)C)=O)(C)C.[OH:24][C:25]([C:28]1[N:29]=[C:30]([CH2:36][CH2:37][CH3:38])[NH:31][C:32]=1[C:33]([OH:35])=[O:34])([CH3:27])[CH3:26].[CH:39]([O:42][C:43]([O:45][CH2:46]Cl)=[O:44])([CH3:41])[CH3:40]>>[OH:24][C:25]([C:28]1[N:29]=[C:30]([CH2:36][CH2:37][CH3:38])[NH:31][C:32]=1[C:33]([O:35][CH2:46][O:45][C:43]([O:42][CH:39]([CH3:41])[CH3:40])=[O:44])=[O:34])([CH3:27])[CH3:26]

참가 물질

4

반응물 3

HCID 14787051Chloromethyl isopropyl carbonateHCID 178440080HCID 178440080, 화합물HCID 178440085HCID 178440085, 화합물

생성물 1

HCID 178440082HCID 178440082, 화합물수율 74.4%

실험 절차

Following a procedure similar to that described in Preparation 22(ii), but using 1.06 g of 4-(1-hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid [prepared as described in Preparation 22(i)] and 0.83 g of isopropoxycarbonyloxymethyl chloride, 1.22 g of the title compound, melting at 144°-146° C., were obtained.

출처 및 근거

ORD 기록
ord-a07536c21b404d71b7582a7297a0e224
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05616599

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