Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 4,6-dimethoxypyrimidine-2-carboxylate → 4,6-Dimethoxypyrimidin-2-carboxylic acid amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 4,6-dimethoxypyrimidine-2-carboxylate | HCID 4449183 | — |
| 반응물 | Ammonia methanol | HCID 21705897 | — |
| 생성물 | 4,6-Dimethoxypyrimidin-2-carboxylic acid amide | HCID 58282682 | 100% |
반응 단계
Ethyl-4,6-dimethoxy-pyrimidin-2-carboxylate (25 g, 1 eq.) in NH3/MeOH (7 M, 15 mL) was irradiated in a microwave reactor at 100° C. for 15 min. The solution was concentrated in vacuo to yield compound 286 as a beige solid in 100% yield. MS (ESI, EI+): m/z=184 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09353100B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-fecba534ef874545876118b99ec14c68 |
| 출처 메모 | uspto-grants-2016_05 |