S-(o-Nitrophenyl)-N-acetyl-D-cysteine → S-(o-Nitrophenyl)-D-cysteine
반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][CH2:11][C@H:12]([C:17]([OH:19])=[O:18])[NH:13]C(=O)C)([O-:3])=[O:2]>S(=O)(=O)(O)O>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][CH2:11][C@H:12]([C:17]([OH:19])=[O:18])[NH2:13])([O-:3])=[O:2]참가 물질
3
반응 조건
- 온도
- 0 °C
실험 절차
A solution of 13.6 g (47.9 mmol) of S-(o-nitrophenyl)-N-acetyl-D-cysteine was refluxed in 57 mL of 18M sulfuric acid (H2SO4) for 1 hour. The bright yellow solution was cooled to 0° C. and concentrated. Ammonium hydroxide (NH4OH) was added to adjust the pH=5.4. The resulting precipitate was filtered and dried to yield 11.6 g (100% ) of product.
후처리
- concentrationconcentrated
- additionAmmonium hydroxide (NH4OH) was added
- filtrationThe resulting precipitate was filtered
- customdried
출처 및 근거
- ORD 기록
- ord-b7167f9134904423ae762dc2aecb6d72
- 출처 데이터셋
- uspto-grants-1997_04
- 특허 번호
- US05618808
반응 노트
불러오는 중…