Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-chloro-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido[5,4-d]pyrimidine → 1,4-Dioxa-8-azaspiro(4.5)decane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-chloro-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido[5,4-d]pyrimidine | HCID 12817020 | — |
| 반응물 | 2-(8-aza-1,4-dioxaspiro[4,5]decan-8-yl)-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido [5,4-d]pyrimidine | HCID 54520012 | — |
| 생성물 | 1,4-Dioxa-8-azaspiro(4.5)decane | HCID 67435 | 58% |
반응 단계
2-(8-aza-1,4-dioxaspiro[4,5]decan-8-yl)-8-(N-benzyl-N-methyl-amino) -4-morpholino-pyrimido [5,4-d]pyrimidine From 2-chloro-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido[5,4-d]pyrimidine and 8-aza-1,4-dioxaspiro-[4,5]decane Yield: 58% of theory, Melting point: 143° C. C25H31N7O3 (477.58)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05618814 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-b91e2a6074184812bdc8055dcbb81d30 |
| 출처 메모 | uspto-grants-1997_04 |