Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(2-Fluoropropoxy)-3-nitropyridine → 2-(2-Fluoropropoxy)pyridin-3-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(2-Fluoropropoxy)-3-nitropyridine | HCID 58413305 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-(2-Fluoropropoxy)pyridin-3-amine | HCID 58413385 | — |
반응 단계
2-(2-fluoropropoxy)-3-nitropyridine (199.97 mg) was dissolved in a mixture of THF (10 ml) and methanol (5 ml). Pd/C (20 mg) was added and the mixture was hydrogenated at room temperature for 4 h and 3 bar. The mixture was concentrated in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08853193B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-cc68b35ccd2f43699ae394ab4323f65f |
| 출처 메모 | uspto-grants-2014_10 |