HCID 58413265, 화합물 → HCID 58413388, 화합물
반응식
[N+:1]([C:4]1[C:5]([O:10][CH2:11][C:12]2([CH2:15][C:16]#[N:17])[CH2:14][CH2:13]2)=[N:6][CH:7]=[CH:8][CH:9]=1)([O-])=O>C(O)(=O)C.C(O)C>[NH2:1][C:4]1[C:5]([O:10][CH2:11][C:12]2([CH2:15][C:16]#[N:17])[CH2:14][CH2:13]2)=[N:6][CH:7]=[CH:8][CH:9]=1참가 물질
4
반응 조건
- 온도
- 100 °C
실험 절차
2-(1-((3-Nitropyridin-2-yloxy)methyl)cyclopropyl)acetonitrile (466 mg) was dissolved in a mixture of glacial acetic acid (4 ml) and ethanol (8 ml). Ferrum (1.1 g) was added and the reaction mixture was heated to 100° C. for 2 h. The mixture was concentrated in vacuo and the residue was dissolved in dichloromethane, extracted with an aqueous solution of K2CO3 (2M) and concentrated in vacuo
후처리
- additionFerrum (1.1 g) was added
- concentrationThe mixture was concentrated in vacuo
- dissolutionthe residue was dissolved in dichloromethane
- extractionextracted with an aqueous solution of K2CO3 (2M)
- concentrationconcentrated in vacuo
출처 및 근거
- ORD 기록
- ord-fbc49b9bc15f46289377696a5fa1cada
- 출처 데이터셋
- uspto-grants-2014_10
- 특허 번호
- US08853193B2
반응 노트
불러오는 중…