Trifluoroacetic acid → HCID 67395207, 화합물
반응식
[C:1]([C:4]1[S:32][C:7]2[N:8]=[CH:9][N:10]=[C:11]([NH:12][C:13]3[CH:30]=[CH:29][C:28]([F:31])=[CH:27][C:14]=3[O:15][CH:16]([CH3:26])[CH2:17][NH:18]C(=O)OC(C)(C)C)[C:6]=2[C:5]=1[CH3:33])(=[O:3])[NH2:2].[F:34][C:35]([F:40])([F:39])[C:36]([OH:38])=[O:37]>ClCCl>[F:34][C:35]([F:40])([F:39])[C:36]([OH:38])=[O:37].[NH2:18][CH2:17][CH:16]([O:15][C:14]1[CH:27]=[C:28]([F:31])[CH:29]=[CH:30][C:13]=1[NH:12][C:11]1[C:6]2[C:5]([CH3:33])=[C:4]([C:1]([NH2:2])=[O:3])[S:32][C:7]=2[N:8]=[CH:9][N:10]=1)[CH3:26]참가 물질
4
실험 절차
tert-Butyl 2-(2-(6-carbamoyl-5-methylthieno[2,3-d]pyrimidin-4-ylamino)-5-fluorophenoxy)propylcarbamate (740 mg) was dissolved in dichloromethane (20 ml) and trifluoroacetic acid (4 ml) was added and the reaction was stirred at room temperature overnight. The reaction was concentrated in vacuo to give the title compound.
후처리
- concentrationThe reaction was concentrated in vacuo