2-(2,2-Difluoroethoxy)pyridin-3-amine → HCID 58413347, 화합물

반응식

[F:1][CH:2]([F:12])[CH2:3][O:4][C:5]1[C:10]([NH2:11])=[CH:9][CH:8]=[CH:7][N:6]=1.[CH3:13][O:14][C:15]([C:17]1[S:26][C:20]2[N:21]=[C:22](Cl)[N:23]=[CH:24][C:19]=2[C:18]=1[CH3:27])=[O:16]>>[CH3:13][O:14][C:15]([C:17]1[S:26][C:20]2[N:21]=[CH:22][N:23]=[C:24]([NH:11][C:10]3[C:5]([O:4][CH2:3][CH:2]([F:1])[F:12])=[N:6][CH:7]=[CH:8][CH:9]=3)[C:19]=2[C:18]=1[CH3:27])=[O:16]

참가 물질

반응물 2

HCID 584133032-(2,2-Difluoroethoxy)pyridin-3-amine

HCID 82104641HCID 82104641, 화합물

생성물 1

HCID 58413347HCID 58413347, 화합물

실험 절차

Prepared analogously to example 28.1 from 2-(2,2-Difluoroethoxy)pyridin-3-amine (171 mg) and Chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester (190 mg)

출처 및 근거

ORD 기록: ord-d8b3b4df632643238237a64600a69fcb
출처 데이터셋: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08853193B2

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