HCID 58413388, 화합물 → HCID 58413386, 화합물

반응식

[NH2:1][C:2]1[C:3]([O:8][CH2:9][C:10]2([CH2:13][C:14]#[N:15])[CH2:12][CH2:11]2)=[N:4][CH:5]=[CH:6][CH:7]=1.[CH3:16][O:17][C:18]([C:20]1[S:29][C:23]2[N:24]=[C:25](Cl)[N:26]=[CH:27][C:22]=2[C:21]=1[CH3:30])=[O:19]>>[C:14]([CH2:13][C:10]1([CH2:9][O:8][C:3]2[C:2]([NH:1][C:27]3[C:22]4[C:21]([CH3:30])=[C:20]([C:18]([O:17][CH3:16])=[O:19])[S:29][C:23]=4[N:24]=[CH:25][N:26]=3)=[CH:7][CH:6]=[CH:5][N:4]=2)[CH2:12][CH2:11]1)#[N:15]

참가 물질

반응물 2

HCID 58413388HCID 58413388, 화합물

HCID 82104641HCID 82104641, 화합물

생성물 1

HCID 58413386HCID 58413386, 화합물

실험 절차

Prepared analogously to example 32.1 using 2-(1-((3-aminopyridin-2-yloxy)methyl)cyclopropyl)acetonitrile (264 mg) and chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester (152 mg).

출처 및 근거

ORD 기록: ord-29e3cf69349947fe8b42029cb49ee0cb
출처 데이터셋: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08853193B2

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