HCID 58413294, 화합물 → HCID 67382004, 화합물

반응식

[F:1][C:2]1([F:14])[CH2:4][CH:3]1[CH2:5][O:6][C:7]1[C:12]([NH2:13])=[CH:11][CH:10]=[CH:9][N:8]=1.[CH3:15][O:16][C:17]([C:19]1[S:28][C:22]2[N:23]=[C:24](Cl)[N:25]=[CH:26][C:21]=2[C:20]=1[CH3:29])=[O:18]>>[F:14][C:2]1([F:1])[CH2:4][CH:3]1[CH2:5][O:6][C:7]1[C:12]([NH:13][C:26]2[C:21]3[C:20]([CH3:29])=[C:19]([C:17]([O:16][CH3:15])=[O:18])[S:28][C:22]=3[N:23]=[CH:24][N:25]=2)=[CH:11][CH:10]=[CH:9][N:8]=1

참가 물질

반응물 2

HCID 58413294HCID 58413294, 화합물

HCID 82104641HCID 82104641, 화합물

생성물 1

HCID 67382004HCID 67382004, 화합물

실험 절차

Prepared analogously to example 32.1 using 2-((2,2-Difluorocyclopropyl)methoxy)pyridin-3-amine (200 mg) and chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester (194 mg).

출처 및 근거

ORD 기록: ord-3b7ee51158f64437bcc61100540036a6
출처 데이터셋: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08853193B2

반응 노트

불러오는 중…