Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-Trifluoromethylpyridinium hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Chloro-4-(trifluoromethyl)pyridine | HCID 144958 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 4-Trifluoromethylpyridinium hydrochloride | HCID 19961898 | — |
반응 단계
A solution of 2-chloro-4-trifluoromethylpyridine (11.6 g) in glacial acetic acid (70 ml), containing 10% palladium on carbon (2.4 g, 21% (w/w)) was hydrogenated at 40 psi for 4 h. Concentrated hydrochloric acid (20 ml) was added and hydrogenation continued for a further 1 h. The catalyst was filtered off and the filtrate evaporated in vacuo to afford 4-trifluoromethylpyridinium hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05618812 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-c04524e8cfc64b38be348babfd49ccb1 |
| 출처 메모 | uspto-grants-1997_04 |