Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Isocyanatothiophene → 1-Cyclopentyl-7-methoxy-3-thiophen-2-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Isocyanatothiophene | HCID 2776375 | — |
| 반응물 | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| 생성물 | 1-Cyclopentyl-7-methoxy-3-thiophen-2-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione | HCID 58329396 | 48.3% |
반응 단계
1-Cyclopentyl-7-methoxy-3-thiophen-2-yl-1H-pyrimido[5,4-c]quinoline-2,4-dione (19 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.10 mmol) and 2-isocyanatothiophene (0.4 mmol) following general procedure C. LCMS: m/z 394 [M+1]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08853226B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-3ed8c6609cdc443cb63da81aa09b73f2 |
| 출처 메모 | uspto-grants-2014_10 |