Acetic Acid → HCID 178497322, 화합물

HRID 533412노트

반응식

HRID 533412 반응식
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:12]([O:14][CH3:15])=[O:13])[CH:10]=2)[N:5]=[CH:4][CH:3]=1.[Cl:16]N1C(=O)CCC1=O.C(O)(=O)C>O>[Cl:16][C:3]1[CH:4]=[N:5][C:6]2[C:11]([C:2]=1[OH:1])=[CH:10][C:9]([C:12]([O:14][CH3:15])=[O:13])=[CH:8][CH:7]=2

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 31398ChlorosuccinimideHCID 178497323HCID 178497323, 화합물

생성물 1

HCID 178497322HCID 178497322, 화합물수율 88%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of methyl 4-hydroxyquinoline-6-carboxylate (2.07 g), N-chlorosuccinimide (1.36 g), and acetic acid (56 mL) was stirred at room temperature for one day. The reaction mixture was diluted with water, and then, the precipitate was collected by filtration to obtain methyl 3-chloro-4-hydroxyquinoline-6-carboxylate (2.13 g).

후처리

  1. filtrationthe precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-6b1b42788d7b4d80a849a9ab49c16cbe
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08853242B2

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