Sulfamide → HCID 11379214, 화합물
반응식
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[O:3][CH:2]1[CH2:10][NH2:11].[S:12](N)([NH2:15])(=[O:14])=[O:13]>O1CCOCC1>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[O:3][CH:2]1[CH2:10][NH:11][S:12]([NH2:15])(=[O:14])=[O:13]참가 물질
4
실험 절차
C-Benzo[1,3]dioxol-2-yl-methylamine (2.94 g, 19.4 mmol) and sulfamide (3.74 g, 38.9 mmol) were combined in dry dioxane (50 mL) and the solution was heated to reflux overnight. The reaction was concentrated and the residue was chromatographed (2% to 10% acetone in dichloromethane) to yield the title compound as a white solid.
후처리
- temperaturethe solution was heated
- temperatureto reflux overnight
- concentrationThe reaction was concentrated
- customthe residue was chromatographed (2% to 10% acetone in dichloromethane)
출처 및 근거
- ORD 기록
- ord-11eb86101c0f45bf96c6e3f8a3d40045
- 출처 데이터셋
- uspto-grants-2014_10
- 특허 번호
- US08853263B2
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