6-Bromo-1-hexene → HCID 11626675, 화합물

HRID 533796노트

반응식

HRID 533796 반응식
[N:1]12[CH2:8][CH2:7][C:4]([C:9]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[OH:10])([CH2:5][CH2:6]1)[CH2:3][CH2:2]2.[Br:23][CH2:24][CH2:25][CH2:26][CH2:27][CH:28]=[CH2:29]>CC#N>[Br-:23].[CH2:29]([N+:1]12[CH2:6][CH2:5][C:4]([C:9]([OH:10])([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)([CH2:3][CH2:2]1)[CH2:7][CH2:8]2)[CH2:28][CH2:27][CH2:26][CH:25]=[CH2:24]

참가 물질

4

반응물 2

HCID 759066-Bromo-1-hexeneHCID 239923851-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol

생성물 1

HCID 11626675HCID 11626675, 화합물수율 67.1%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

Following the general procedure outlined in Example 3, 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0637 g, 0.217 mmol) and 6-bromo-1-hexene (0.050 mL, 0.373 mmol) in 2 CH3CN/3 CHCl3 (5.0 mL) were reacted to give the desired product (0.0664 g, 67.1%). EI-MS m/z 376(M+) Rt (1.90 min).

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-a90b691bca964f76b7432be4168b9be0
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08853404B2

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