Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromophenol → Phenol, 4-(3-pyridinyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromophenol | HCID 7808 | — |
| 반응물 | 3-(Tributylstannyl)pyridine | HCID 3483848 | — |
| 촉매 | HCID 178418476 | HCID 178418476 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | Phenol, 4-(3-pyridinyl)- | HCID 153040 | 60% |
반응 단계
26.8 g of 4-bromophenol was taken under protective gas in 1000 ml of dioxane, mixed with 90 g 3-tributylstannylpyridine [preparation according to litt.: Org. Magn. Resonance, 7 (1975), 610] and 11.1 g of bis-(triphenylphosphine)-palladium(II) chloride and refluxed for 15 hours. After concentration by evaporation in a vacuum and purification on silica gel, 15.92 g of the above compound is isolated.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05244886 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-7844a06e09664a17934167953fba756b |
| 출처 메모 | uspto-grants-1993_09 |