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[C:1](OC1C2C=CC(C#CC3C=CC(C(OCC)=O)=CC=3)=CC=2C(C)(C)CC=1)(=[O:3])[CH3:2].[CH3:30][C:31]1([CH3:53])[C:40]2[CH:39]=[CH:38][C:37]([C:41]#[C:42][C:43]3[CH:51]=[CH:50][C:46]([C:47]([OH:49])=[O:48])=[CH:45][CH:44]=3)=[CH:36][C:35]=2[C:34](=[O:52])[CH2:33][CH2:32]1>>[C:1]([O:52][C:34]1[C:35]2[CH:36]=[C:37]([C:41]#[C:42][C:43]3[CH:44]=[CH:45][C:46]([C:47]([OH:49])=[O:48])=[CH:50][CH:51]=3)[CH:38]=[CH:39][C:40]=2[C:31]([CH3:53])([CH3:30])[CH2:32][CH:33]=1)(=[O:3])[CH3:2]참가 물질
3
실험 절차
Employing the same general procedure as for the preparation of ethyl 4-[(5-acetoxy-7,8-dihydro-8,8-dimethylnaphth-2-yl)ethynyl]benzoate (Compound 105), 100.0 mg (0.31 mmol) of 4-[(5,6,7,8-tetrahydro-8,8-dimethyl-5-oxonaphth-3-yl)ethynyl]benzoic acid (Compound 8) was converted into the title compound (white solid) using 0.08 ml (0.94 mmol) of acetic anhydride and 30 mg (0.16 mmol) of p-toluenesulfonic acid.
출처 및 근거
- ORD 기록
- ord-92e848217e1c48d4b16f8fd5e84aeed9
- 출처 데이터셋
- uspto-grants-1997_04
- 특허 번호
- US05618931
연결된 노트
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