Benzyl Alcohol → (R)-3-(6-Benzyloxy-pyridin-3-yloxy)-pyrrolidin-2-one
반응식
[CH:1]1([CH2:4][CH2:5][O:6][C:7]2[N:12]=[CH:11][C:10]([O:13][C@@H:14]3[CH2:18][CH2:17][NH:16][C:15]3=[O:19])=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[C:20]1(CO)C=CC=C[CH:21]=1.BrC1C=CC(F)=NC=1.O[C@H]1CCNC1=O>>[CH2:5]([O:6][C:7]1[N:12]=[CH:11][C:10]([O:13][C@@H:14]2[CH2:18][CH2:17][NH:16][C:15]2=[O:19])=[CH:9][CH:8]=1)[C:4]1[CH:1]=[CH:3][CH:2]=[CH:21][CH:20]=1참가 물질
5
실험 절차
Following the sequence described for (R)-3-[6-(2-cyclopropyl-ethoxy)-pyridin-3-yloxy]-pyrrolidin-2-one, the title compound was prepared from phenyl-methanol, 5-bromo-2-fluoro-pyridine and (S)-3-hydroxy-pyrrolidin-2-one. MS ESI+: m/z=285 [M+H]+.
출처 및 근거
- ORD 기록
- ord-af86e7dfd20a4ca79a9a87c23271b4b0
- 출처 데이터셋
- uspto-grants-2014_10
- 특허 번호
- US08853412B2
반응 노트
불러오는 중…