Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 2-Iodobenzene n-propylsulfonylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Propyl isocyanate | HCID 61033 | — |
| 반응물 | 2-Iodobenzene-1-sulfonamide | HCID 2824892 | — |
| 반응물 | Acetone diisopropyl ether | HCID 22221350 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-Iodobenzene n-propylsulfonylurea | HCID 67709745 | — |
반응 단계
To a stirred solution of 2-iodo benzene sulfonamide (4 g) in acetone (40 mi) solid K2CO3 (3.92 g) is added in one portion and the mixture is refluxed under N2 -atmosphere, n-propyl isocyanate is added dropwise to the heated mixture. After 2 hours reflux, the reaction is cooled to room temperature and concentrated to dryness. Water (200 ml) is added and the cooled mixture is acidified with 2N HCl to pH 4 and filtered. The precipitate obtained is recristallised with acetone/isopropyl ether mixture to give 4.1 g solid of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05618975 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-18fec9a30f8d426199d4e419529c510e |
| 출처 메모 | uspto-grants-1997_04 |