Methyl 17beta-benzoyl-estra-1,3,5(10)-triene-3-carboxylate → 17beta-(3,4-Methylenedioxybenzoyl)-estra-1,3,5(10)-triene-3-carboxylic acid
반응식
[C:1]([C@H:9]1[CH2:14][CH2:13][C@H:12]2[C@H:15]3[C@H:24]([CH2:25][CH2:26][C@:10]12[CH3:11])[C:23]1[CH:22]=[CH:21][C:20]([C:27]([O:29]C)=[O:28])=[CH:19][C:18]=1[CH2:17][CH2:16]3)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:31]1[O:39]C2C=CC([Mg]Br)=CC=2[O:32]1>>[CH2:31]1[O:39][C:5]2[CH:4]=[CH:3][C:2]([C:1]([C@H:9]3[CH2:14][CH2:13][C@H:12]4[C@H:15]5[C@H:24]([CH2:25][CH2:26][C@:10]34[CH3:11])[C:23]3[CH:22]=[CH:21][C:20]([C:27]([OH:29])=[O:28])=[CH:19][C:18]=3[CH2:17][CH2:16]5)=[O:8])=[CH:7][C:6]=2[O:32]1참가 물질
3
실험 절차
The title compound was prepared by the method of Example 19 (iv) by replacing benzylmagnesium chloride with 3,4-methylenedioxyphenylmagnesium bromide.
출처 및 근거
- ORD 기록
- ord-44631a82b5b94d1fa39a8991bac6e21a
- 출처 데이터셋
- uspto-grants-1997_04
- 특허 번호