Glyceryl Allyl Ether → 4-((allyloxy)methyl)-N,N-dimethyl-1,3,2-dioxarsolan-2-amine

HRID 534662

반응식

HRID 534662 반응식
[CH3:1][N:2]([As:4](N(C)C)N(C)C)[CH3:3].[CH2:11]([O:14][CH2:15][CH:16]([OH:19])[CH2:17][OH:18])[CH:12]=[CH2:13]>CCCCCC>[CH2:11]([O:14][CH2:15][CH:16]1[CH2:17][O:18][As:4]([N:2]([CH3:3])[CH3:1])[O:19]1)[CH:12]=[CH2:13]

참가 물질

4

반응물 2

HCID 78950Glyceryl Allyl EtherHCID 165514N-[bis(dimethylamino)arsanyl]-N-methylmethanamine

생성물 1

HCID 867176874-((allyloxy)methyl)-N,N-dimethyl-1,3,2-dioxarsolan-2-amine

시약·촉매·용매 1

HCID 8058Hexane용매

실험 절차

is formed when at room temperature, about 0.5 g (0.445 mL, 2.414 mmol, 1.1 equivalents) of tris(dimethylamino)arsine (TDMA), is added to about 10 mL dry hexane in a 25 mL round-bottom flask, and then about 0.29 g (0.27 mL, 2.19 mmol, 1.0 equivalents) of 3-(allyloxy)propane-1,2-diol is added dropwise into the system. The mixture is heated to reflux under nitrogen for about one hour, and then cooled to room temperature. Removal of the solvent in vacuum gives crude 4-((allyloxy)methyl)-N,N-dimethyl-1,3,2-dioxarsolan-2-amine as an oil.

후처리

  1. customis formed when at room temperature
  2. temperatureThe mixture is heated
  3. temperatureto reflux under nitrogen for about one hour
  4. customRemoval of the solvent in vacuum

출처 및 근거

ORD 기록
ord-d965bae987d640fdb842bd4418f8dac3
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08853438B2

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