Sodium Carbonate → 9-(Naphthalen-2-yl)anthracene

HRID 534811노트

반응식

HRID 534811 반응식
Br[C:2]1[C:3]2[C:8]([CH:9]=[C:10]3[C:15]=1[CH:14]=[CH:13][CH:12]=[CH:11]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.B(O)O.C(=O)([O-])[O-].[Na+].[Na+]>C1(C)C=CC=CC=1>[CH:4]1[C:3]2[C:2](=[CH:15][CH:10]=[CH:9][CH:8]=2)[CH:6]=[CH:5][C:4]=1[C:3]1[C:2]2[C:11]([CH:10]=[C:9]3[C:8]=1[CH:7]=[CH:7][CH:6]=[CH:5]3)=[CH:12][CH:13]=[CH:14][CH:15]=2

참가 물질

5

반응물 3

HCID 10340Sodium CarbonateHCID 61668Boronic AcidHCID 740629-Bromoanthracene

생성물 1

HCID 2644169-(Naphthalen-2-yl)anthracene수율 173.5%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

22.5 g of 9-bromoanthracene, 15.8 g of 2-naphthelene boronic acid and 2.0 g of tetrakis(triphenylphophine)palladium were mixed, followed by argon displacement. After adding 150 ml of toluene and 140 ml of 2M sodiumcarbonate aqueous solution thereto, it was refluxed on heating for 7 hours. After standing to cool, the crystal precipitated was filtrated it was washed by ethanol and toluene. The crystal obtained was recrystallized in toluene, followed by filtering and drying, and then 23.1 g of 9-(naphthalene-2-yl)anthracene was obtained (yield: 87%).

후처리

  1. temperatureit was refluxed
  2. temperatureon heating for 7 hours
  3. temperatureto cool
  4. customthe crystal precipitated
  5. filtrationwas filtrated it
  6. washwas washed by ethanol and toluene
  7. customThe crystal obtained
  8. customwas recrystallized in toluene
  9. filtrationby filtering
  10. customdrying

출처 및 근거

ORD 기록
ord-3786fd58829b4418912ab428e35d8e12
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08853675B2

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