Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Piperidin-2-ylethanol → 5,11-Dihydro-11-ethyl-2-[2-(hydroxyethyl)piperidin-1-yl]-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Piperidin-2-ylethanol | HCID 15144 | — |
| 반응물 | Dipyridodiazepinone deriv. 15 | HCID 463144 | — |
| 생성물 | 5,11-Dihydro-11-ethyl-2-[2-(hydroxyethyl)piperidin-1-yl]-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one | HCID 53849070 | — |
반응 단계
The title compound, m.p. 234°-237° C., was synthesized from 2-chloro-5,11-dihydro-11-ethyl-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one and 2-(hydroxyethyl)piperidine using procedures analogous to those described above, except that the mixture was heated at reflux for 1.25 hrs, and the product was crystallized from ethyl acetate/ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05620974 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-b7f1469f3d084a4ab9c68b1dfc083a28 |
| 출처 메모 | uspto-grants-1997_04 |